Aptamer Details

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Human Breast Cancer Xenografts (RGD-4C) (ID# 7608)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.

Aptamer Chemistry: Peptide

Target: Human Breast Cancer Xenografts

Antigen/Target Category: Tissue

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: In vivo mice.

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 9

Molecular Weight: 1103.34

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Arap et al. "Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model." Science, 279(1998): 377-380.

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