Aptamer Details

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Peritoneal tumors of gastric cancer (ID# 7643)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.

Aptamer Chemistry: Peptide

Target: Peritoneal tumors of gastric cancer

Antigen/Target Category: Tissue

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: In vivo in mice. Washed with PBS containing 0.5% Tween-20 sorbitan monolaurate.

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Comments: KLP motif showed homology to laminin-5, which binds to a3??1 integrin, suggesting that this might be the target of the aptamer.

Sequence ():

Length: 10

Molecular Weight: 1252.56

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Akita et al. "Identification of oligopeptides binding to peritoneal tumors of gastric cancer." Japanese Cancer Association, 97(2006): 1075-1081.

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