Aptagen, LLC
            
                
                    
                                                    
                                            
                                    
                
                                            
            
            
            
            
        
    Lead (Pb) binding aptamer (ID# 7709)
                                            
                            
                            DNA
                        
                    
                                            
                            
                            Lead (Pb)
                        
                    
                                            
                            
                            Other
                        
                    
                                            
                            
                            1 nM (reported value)
                        
                    
                                            
                            
                            pH 7.0, 20 mM NaNO3, 8 mM Tris nitrate, 100 μM NaCN, 25 °C
                        
                    
                                            
                            
                            N/A°C
                        
                    
                    
                        
                        
                                                            NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.                         
                    
                    
                                            
                            
                            Aptamer forms a G-quartet in the presence of lead ions.
                        
                                    
                
                
                    5'-dGpdGpdTpdTpdGpdGpdTpdGpdTpdGpdGpdTpdTpdGpdGp-3'
                
                
                    
                
                                    
                        
                        
                            
                    
                
                
                
            
            
        
                
                        
                        15
                    
                
                                    
                        
                        4726.13
                    
                            
                                    
                        
                        143300
                    
                            
                
                
                Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
B-F Ye et al. "Colorimetric photonic hydrogel aptasensor for the screening of heavy metal ions." Nanoscale 4(2012): 5998-6003.
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