Aptamer Details

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Human Transferrin Receptor (T7) (ID# 7815)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.

Aptamer Chemistry: Peptide

Target: Human Transferrin Receptor (hTfR)

Antigen/Target Category: Protein

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: Serum-free Opti-MEM.

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Does not bind to mouse TfR.

Comments: This peptide aptamer is internalized through receptor-mediated endocytosis.

Sequence ():

Length: 7

Molecular Weight: 939.15

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

J. H. Lee et al. Receptor mediated uptake of peptides that bind the human transferrin receptor. Eur. J. Biochm. 268(2001): 2004-2012.

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