Aptamer Details

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Fcγ receptor IIIα / CD16α (CLN0020) (ID# 7859)

Aptamer Chemistry: DNA

Target: FcγrIIIα / FcgrIIIa / CD16a

Antigen/Target Category: Protein

Affinity (Kd): 22 nM (reported value)

Binding Conditions/Buffer: Binding Buffer: DPBS with 0.05% BSA

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Did not bind to CD16β.

Sequence ():

Length: 60

Molecular Weight: 18824.27

Extinction Coefficient: 606600

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Boltz A, Plater B, Hock B, et al. (2011) Bi-specific Aptamers Mediating Tumour Cell Lysis. J Biol Chem 286: 21896-21905

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