Aptamer Details

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S3 (ID# 8057)

Aptamer Chemistry: DNA

Target: CD109

Antigen/Target Category: Protein

Affinity (Kd): 10.5332 - 13.3326 nM (reported value)

Binding Conditions/Buffer: Dulbecco’s phosphate buffered saline (D-PBS, Ca2+/Mg2+-free) supplemented with 4.5 g/L of glucose and 5 mM of MgCl2

Binding Temp: 4°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 44

Molecular Weight: 13834

Extinction Coefficient: 437600

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Xiong, H., Yan, J., Cai, S., He, Q., Peng, D., Liu, Z., & Liu, Y. (2019). Cancer protein biomarker discovery based on nucleic acid aptamers. International Journal of Biological Macromolecules. doi:10.1016/j.ijbiomac.2019.03.165

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