Aptagen, LLC
RhD antigen‑specificity 1 (ID# 8105)
![](https://www.aptagen.com/wp-content/uploads/RhD1.jpg)
DNA
RhD+ red blood cells
Cells
580.5±142.0 nM (reported value)
10 mM Tris-HCl, 50 mM KCl, pH 9.0), 1.5 mM MgCl2, 400 µM each
dNTP, 2.5 U Taq DNA polymerase (Promega Corporation), and 50 pmol each biotinylated primer
25°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdGpdCpdCpdTpdGpdGpdTpdCpdTpdGpdTpdTpdApdGpdCpdCpdGpdGpdGpdTpdApdGpdCpdApdGpdCpdCpdCpdCpdGpdGpdCpdApdCpdCpdTpdApdTpdTp-3'
![](/wp-content/uploads/apta-sequence-abbr.png)
40
12280.9
363800
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Zhang Y, Xu H, Wang X, Wang L, Liu R, Li L, Zhou H. Single‑strained DNA aptamers mask RhD antigenic epitopes on human RhD+ red blood cells to escape alloanti‑RhD immunological recognition. Mol Med Rep. 2020 Apr;21(4):1841-1848. doi: 10.3892/mmr.2020.10985. Epub 2020 Feb 12. PMID: 32319623; PMCID: PMC7057830.
Have your aptamer oligo synthesized ORDER
We are always looking for ways to improve. Please tell us what you think.