Aptamer Details

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Sp1 (ID# 8152)

Aptamer Chemistry: DNA

Target: Shigella sonnei

Antigen/Target Category: Other

Affinity (Kd): 5.98 nM (reported value)

Binding Conditions/Buffer: Tris BB

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: binding with S. sonnei is six times greater than other, related bacteria species.

Comments: Dual aptamer with Sp20

Sequence ():

Length: 80

Molecular Weight: 24547.59

Extinction Coefficient: 720600

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.

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