Aptamer Details

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H2 (ID# 8226)

Aptamer Chemistry: DNA

Target: HER-2

Antigen/Target Category: Protein

Affinity (Kd): 270 nM (reported value)

Binding Conditions/Buffer: Binding buffer: 100 mM NaCl, 20 mM Tris–HCl, pH 7.6, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% Tween 20

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 54

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

"In vitro HER2 protein-induced affinity dissociation of carbon nanotube-wrapped anti-HER2 aptamers for HER2 protein detection" J. H. Niazi, S. K. Verma, S. Niazi and A. Qureshi, Analyst, 2014 DOI: https://doi.org/10.1039/C4AN01665C

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