Aptagen, LLC
Celiac disease Aptamer (Gli1) (ID# 8791)
DNA
33-mer peptide (immunodominant fragment from α2-gliadin)
Peptide
102 ± 11 nM (reported value)
50 mM TRIS-HCl, 0.25 M NaCl, 5mM MgCl2
30°C
N/A
None
5'-dCpdTpdApdGpdGpdCpdGpdApdApdApdTpdApdTpdApdGpdCpdTpdApdCpdApdApdCpdTpdGpdTpdCpdTpdGpdApdApdGpdGpdCpdApdCpdCpdCpdApdApdTp-3'
40
13200
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Gonzalez S., et. al. "Aptamer Binding to Celiac Disease-Triggering Hydrophobic Proteins A Sensitive Gluten Detection Approach." 2014. Analytical Chemistry 86: 2733-39. González S., Álvarez N., Ordieres O. & Castañón M. (2015). "Sensitive gluten determination in gluten-free foods by an electrochemical aptamer-based assay." Volume 407, pages 6021–6029. https://doi.org/10.1007/s00216-015-8771-6
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