Aptagen, LLC
RNA 14-16 (ID# 9005)
RNA
p68 oncogenic helicase
Protein
13.8 nM (reported value)
Biotinylated RNA motifs immobilized on streptavidin
magnetic beads were incubated with tumor tissue extracts and
washed. RNA-bound proteins were then eluted in high salt solution and resolved electrophoretically before Coomassie blue staining .
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
rGprGprGprAprGprGprAprCprGprAprUprGprCprGprGprCprAprGprUprGprCprCprCprAprAprCprCprGprGprAprAprCprAprAprCprAprAprCprCprAprCprCprGprGprCprGprGprCprUprCprCprUprGprCprUp
55
16894.9 g/mole
514600 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Mi J, Liu Y, Rabbani ZN, Yang Z, Urban JH, Sullenger BA, Clary BM. In vivo selection of tumor-targeting RNA motifs. Nat Chem Biol. 2010 Jan;6(1):22-4. doi: 10.1038/nchembio.277. Epub 2009 Nov 29. PMID: 19946274; PMCID: PMC2795795.
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