Aptagen, LLC
A23P6 (ID# 9183)
DNA
IL-23 (P19 subunit)
Protein
2.139 nM (reported value)
Binding Buffer: 50 mM phosphate, 150 mM NaCl, pH 7.8
37°C
Heated at 95°C for 5 min, Cooled to room temperature for 30 min before binding studies
Showed strong binding to IL-23 (P19 subunit) , no reported cross-reactivity with IL-12 or IL-27 (which share the P40 subunit)
Identified through TA cloning of SELEX-selected aptamers
High affinity for IL-23, making it a candidate for biomarker detection
Predicted to form stable loop structures
5'-dTpdGpdGpdGpdGpdTpdApdGpdGpdGpdTpdGpdGpdTpdApdGpdTpdTpdGpdGpdGpdApdGpdGpdGpdTpdApdGpdGpdGpdTpdGpdGpdTp-3'
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
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