Aptagen, LLC
A23P15 (ID# 9185)
DNA
IL-23 (P19 subunit)
Protein
2.88 nM (reported value)
Binding Buffer: 50 mM phosphate, 150 mM NaCl, pH 7.8
37°C
Heated at 95°C for 5 min, cooled to room temperature for 30 min before binding studies
Selective binding to IL-23 (P19 subunit), no cross-reactivity with non-target proteins
Identified as one of the three highest-affinity aptamers from SELEX
Holds potential for therapeutic inhibition of IL-23 signaling in inflammatory diseases
5'-dGpdGpdTpdApdGpdGpdGpdTpdGpdGpdTpdApdGpdTpdTpdGpdGpdGpdApdGpdGpdGpdTpdApdGpdGpdGpdTpdGpdGpdTpdApdGpdTp-3'
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
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