Aptamer Details

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Acetylcholine Receptor Antibody (mAB198) (SE RNA VII) (ID# 7482)

Aptamer Chemistry: DNA

Target: Acetylcholine Receptor Antibody (mAB198)

Antigen/Target Category: Protein

Affinity (Kd): 60 nM (reported value)

Binding Conditions/Buffer: Binding Buffer (30mM Tris-HCl (pH 7.5), 150 mM NaCl, 10mM MgCl2, 2mM dithiothreitol, 1% BSA)

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 48

Molecular Weight: 28339.52

Extinction Coefficient: 455500

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Lee, Seong-Wook and Sullenger, Bruce. "Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies." Nature Biotechnology, 15 (1997): 41-45.

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