Aptamer Details

Back to Search Results

API7-4 (ID# 9205)

DNA
Small Organic
< 10 nM (reported value)
Binding buffer: PBST (Phosphate Buffered Saline with Tween 20) + 5 mM Mg²⁺
37°C
Not explicitly mentioned in the paper. However, the aptamers were likely refolded by heating and cooling, a common practice in aptamer studies, though the specific program is not detailed.
Specifically binds to HuNoV GII.4 VLP. Does not react with other diarrhea-causing pathogens or unrelated proteins, such as: E. coli lysate Caco2 cell lysate EV71 (Enterovirus 71) Coronavirus S protein Astrovirus Confirmed by dot blotting and ELASA (Enzyme-Linked Aptamer Sorbent Assay).

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Prasad BVV, Hardy ME, Dokland T, Bella J, Rossmann MG, Estes MK. X-ray crystallographic structure of the Norwalk virus capsid. Science. 1999;286(5438):287–290. doi:10.1126/science.286.5438.287

Have your aptamer oligo synthesized ORDER