Aptamer Details

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Beta 2-Integrin (D20) (ID# 7543)

Aptamer Chemistry: RNA

Target: Beta 2-Integrin

Antigen/Target Category: Protein

Affinity (Kd): 500 nM (reported value)

Binding Conditions/Buffer: Binding Buffer (4.3 mM K2HPO4, 1.4 mM NaH2PO4, 150 mM NaCl, 1.0 mM MgCl2, 0.1 uM CaCl2)

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 73

Molecular Weight: 23599.21

Extinction Coefficient: 700300

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Blind, M., et al. "Cytoplasmic RNA modulators of an inside-out signaltransduction cascade." Proceedings of National Academy of Sciences of the United States of America, 96(1999):3606ƒ??3610.

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