Aptamer Details

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Bfl-1 Anti-Apoptotic Protein (Apt27) (ID# 7776)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.

Aptamer Chemistry: Peptide

Target: Bfl-1 Anti-Apoptotic Ptrotein

Antigen/Target Category: Protein

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: N/A

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Does not interact wit Bcl-2, Bcl-xL, or Mcl-1 in yeast.

Sequence ():

Length: 13

Molecular Weight: 1547

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Brien et al. "Characterization of Aptamers Targeting Bfl-1 Anti-Apoptotic Protein." Biochemistry, 50, (2011): 5120-5129.

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