Aptamer Details

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C10 (ID# 8077)

Aptamer Chemistry: DNA

Target: Rituximab

Antigen/Target Category: Protein

Affinity (Kd): 17.6 nM (reported value)

Binding Conditions/Buffer: 20 mM Tris pH 7.6, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% v/v Tween 20

Binding Temp: 22°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 40

Molecular Weight: 12348

Extinction Coefficient: 386600

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Kohlberger M, Wildner S, Regl C, Huber CG, Gadermaier G. Rituximab-specific DNA aptamers are able to selectively recognize heat-treated antibodies. PLoS One. 2020 Nov 5;15(11):e0241560. doi: 10.1371/journal.pone.0241560. PMID: 33151990; PMCID: PMC7644011.

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