Aptamer Details

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cAMP (ID# 7512)

Aptamer Chemistry: RNA

Target: cAMP

Antigen/Target Category: Small Organic

Affinity (Kd): 10 µM (reported value)

Binding Conditions/Buffer: Binding Buffer (20 mM Tris-HCl (pH 7.5 at 23 °C), 450 mM NaCl, 100 mM KCl, 10 mM MgCl₂, 1 mM MnCl₂, and 5 mM CaCl₂)

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 31

Molecular Weight: 10044.17

Extinction Coefficient: 316000

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Kozumi and Breaker. "Molecular Recognition of cAMP by an RNA Aptamer." Biochemistry, 39 (2000): 8983-8992.

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