Aptamer Details

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Daunomycin (10.10v) (ID# 7558)

Aptamer Chemistry: DNA

Target: Daunomycin

Antigen/Target Category: Small Organic

Affinity (Kd): 272 nM (reported value)

Binding Conditions/Buffer: Binding Buffer ((20 mM Trisƒ??HCl [pH 7.4], 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, 1 mM CaCl2, and 0.05% [v/v] Tween 20)

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 41

Molecular Weight: 12873.4

Extinction Coefficient: 405800

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Wochner, et al. "A DNA aptamer with high affinity and specificity for therapeutic anthracyclines." Analytical Biochemistry, 373(2008): 34-42.

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