Aptagen, LLC
Diversely Functionalized Human alpha-Thrombin Aptamer (ID# 8028)
DNA
Human alpha-Thrombin
Protein
1.6 nM (reported value)
20 mM Tris-HCl pH 7, 140 mM NaCl, 5mM KCl, 1 mM MgCl2, 1 mM CaCl2
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
This aptamer is highly functionalized. See paper for details.
GGATCCGAGCTCCACGTG ACTGC ATCTA ATTCC AACCT ATCCA ATCCT ATTCG ATGCT TGCGACGGCAGGCGAATC
![](/wp-content/uploads/apta-sequence-abbr.png)
76
23.338 kDa
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
DOI: 10.1021/jacs.7b07241 J. Am. Chem. Soc. 2017, 139, 13977−13980
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