Aptamer Details

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ErbB2 Tyrosine Kinase Receptor (Ph7-2) (ID# 7779)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.

Aptamer Chemistry: Peptide

Target: ErbB2 Tyrosine Kinase Receptor

Antigen/Target Category: Protein

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: N/A

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Binds strongly to breast cancer cell lines SKBR3 and T47D.

Sequence ():

Length: 7

Molecular Weight: 911.12

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Shadidi and Sioud. "Identification of Novel Peptides for the Specific Delivery of Therapeutics into Cancer Cells." The FASEB Journal, 2, (2003): 256-8.

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