Aptagen, LLC
Estrogen Aptamer (AptER-1) (ID# 7879)
RNA
Apo-estrogen receptor alpha
Protein
16 nM (reported value)
12 mM HEPES/pH 7.6, 150 mM NaCl, and 10 mM MgCl2
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dGpdGpdGpdCpdApdGpdApdCpdGpdCpdApdCpdCpdGpdCpdGpdApdApdCpdApdApdApdApdCpdGpdCpdApdApdGpdApdCpdApdGpdApdGpdTpdGpdCpdCpdGpdApdCpdApdApdGpdApdGpdCpdApdCpdTpdApdCpdApdApdGpdCpdTpdTpdCpdTpdGpdCpdCpdCp
65
20019.01
635300
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Xu, D., Chatakonda, V., Kourtidis, A., Conklin, D., and Shi, H. "In Search of Novel Drug Target Sites on Estrogen Receptors Using RNA Aptamers." Nucleic acid therapeutics 24.3 (2014): 227-38.
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