Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
ex-50.T (ID# 8143)
2'-F-RNA
Breast cancer exosomes
Other
0.8 nM (reported value)
For Binding Assays on Exosomes:
200 nM of aptamer in 1X PBS
PBS buffer used to wash
For Binding Assays on Cells:
200 nM of aptamer in serum-free medium
Serum-free medium used to wash
37°C
N/A
Specific for breast cancer exosomes. Able to discriminate from two other cancer exosome types. Does not react with HSA
5'-fUprGpfUprGprGpfCprAprGpfUpfUprAprAprGprAprApfUprAprGprApfUpfCpfUpfUpfCprGpfCpfUprGpfCprGprApfUpfUp-3'
33
10.652
333200
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
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