Aptamer Details

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H5 Avian Influenza Virus (HAS15-5) (ID# 7617)

Aptamer Chemistry: RNA

Target: Hemagglutinin of the Subtype H5 Avian Influenza Virus

Antigen/Target Category: Protein

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: Wash Buffer (PBS Buffer (pH 7.4), 140 mM NaCl, and 2.7 mM KCl)

Binding Temp: RT°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Comments: This aptamer binds to the hemagglutinin receptor-binding domain and suppresses RBC agglutination.

Sequence ():

Length: 90

Molecular Weight: 29103.68

Extinction Coefficient: 916900

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Park et al. "Selection of an Antiviral RNA Aptamer Against Hemagglutinin of the Subtype H5 Avian Influenza Virus." Nucleic Acid Therapeutics, 21(2011): 395-402.

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