Aptamer Details

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Hepatitis C Virus RdRp (r10/43) (ID# 7476)

Aptamer Chemistry: DNA

Target: Hepatitis C Virus RdRp

Antigen/Target Category: Protein

Affinity (Kd): 1.3 nM (reported value)

Binding Conditions/Buffer: Binding buffer: HEPES-buffered saline containing 1 mM CaCl₂, 2.7 mM MgCl₂, and 0.005% surfactant P-20 (HBS-CKM)

Binding Temp: RT°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 83

Molecular Weight: 25933.89

Extinction Coefficient: 827900

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Jones et al. "High-Affinity Aptamers to Subtype 3a Hepatitis C Virus Polymerase Display Genotypic Specificity." Antimicrobial Agents and Chemotherapy, 50 (2006): 3019-3027.

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