Aptagen, LLC
Heteroaryl dihydropyrimidine (Aptamer 21) (ID# 7596)
RNA
Heteroaryldihydropyrimidine (HAP)
Small Organic
50 nM (reported value)
Selection buffer: 150 mM NaCl, 5 mM MgCl2, and 50 mM HEPES (pH 7.4)
20°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
RNA was refolded prior to selection process.
5'-rGprGprGprUprAprGprGprCprCprAprGprGprCprAprGprCprCprAprAprCprUprAprGprCprGprAprGprAprGprCprUprUprAprAprAprUprCprUprCprUprGprAprGprCprCprCprGprAprGprAprGprGprGprUprUprCprAprGprUprGprCprUprGprCprUprUprAprUprGprUprGprGprAprCprGprGprCprUprUp-3'
79
25553.41
774800
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Lau et al. "Evolution and Protein Packaging of Small-Molecule RNA Aptamers." ACS NANO, 5(2011): 7722-7729.
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