Aptagen, LLC
Histone H3R8Me2sym (Clone 1) (ID# 7615)
RNA
Histone H3R8Me2sym
Peptide
12 nM (reported value)
N/A
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Truncated versions of the aptamer were investigated, but exhibited lower affinities for the target.
5'-rGprGprGprAprCprGprCprGprUprGprGprUprAprCprCprGprAprUprGprGprGprUprCprAprGprCprAprUprGprUprAprGprCprCprAprGprGprCprAprGprGprGprCprCprGprUprGprUprGprAprGprCprUprUprGprUprGprCprUprGprAprUprGprUprGprAprGprCprUprUprCprCprGprCprGprGprGprGprAprUprCp-3'
81
26323.83
784200
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Hyun et al. "An RNA Aptamer That Selectively Recognizes Symmetric Dimethylation of Arginine 8 in the Histone H3 N-Terminal Peptide." Nucleic Acid Therapeutics, 21 (2011): 157-163.
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