Aptamer Details

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HPA-2 (ID# 8107)

Aptamer Chemistry: DNA

Target: Helicobacter pylori

Antigen/Target Category: Other

Affinity (Kd): 19.3 ± 3.2 nM (reported value)

Binding Conditions/Buffer: 100 mM NaCl, 5 mM KCl, 50 mM Tris−HCl, and 1 mM MgCl2, pH 7.5

Binding Temp: 30°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 40

Molecular Weight: 12297

Extinction Coefficient: 385700

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Wu, Hangjie et al. “Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA Aptamers.” ACS omega vol. 6,5 3771-3779. 21 Jan. 2021, doi:10.1021/acsomega.0c05374

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