Aptagen, LLC
i-6 (ID# 8154)
DNA
Glycan modification
Other
29.5 µM (reported value)
40 mM Tris-HCl, 240 mM NaCl, 10 mM KCl, 2 mM MgCl2, 2 mM CaCl2, and 0.01% Tween-20 in nuclease-free water
22°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Contains indole-modified bases. See reference article and its supplemental information for details.
'5-dApdGpdCpdApdGpdCpdApdCpdApdGpdApdGpdGpdTpdCpdApdGpdApdTpdGpdApdTpdCpdTpdCpdGpdTpdGpdTpdGpdTpdTpdTpdGpdGpdTpdTpdTpdTpdApdGpdApdTpdTpdTpdTpdTpdGpdGpdApdApdApdTpdTpdApdTpdGpdApdTpdTpdCpdCpdTpdGpdTpdTpdGpdGpdTpdCpdCpdCpdTpdApdTpdGpdCpdGpdTpdGpdCpdTpdApdCpdCpdGpdTpdGpdApdAp
-'3
90
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Discovery of indole-modified aptamers for highly specific recognition of protein glycoforms Alex M. Yoshikawa, Alexandra Rangel, Trevor Feagin, Elizabeth M. Chun, Leighton Wan, Anping Li, Leonhard Moekl, Michael Eisenstein, Sharon Pitteri, H. Tom Soh bioRxiv 2021.03.13.435263; doi: https://doi.org/10.1101/2021.03.13.435263
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