Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Interleukin-17A/F (IL-17A/F) (APTAF42) (ID# 7525)
2'-F-RNA
Human Interleukin-17A/F
Protein
72.2 nM (reported value)
Binding Buffer (145 mM sodium chloride, 5.4 mM potassium chloride, 0.8 mM magnesium chloride, 1.8 mM calcium chloride, 20 mM Trisƒ??HCl (pH 7.6) supplemented with 0.05% Tween20
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
See also the optimized version: AptAF42dope1.
5'-rGprGprGpfCpfUprAprGpfCpfUprGprApfUpfCprGpfUprApfCpfCpfCprAprGpfUprAprGpfCprGpfUprGprGpfCprApfUprGprGprGprGpfUprGpfCpfCpfUprAprGpfUpfCprGprGprGpfCprGprApfUprApfCpfUprAprApfCprAprGpfCpfUprAprApfCprApfCpfCpfCp-3'
69
22313.31
670800
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Adachi, H., et al. "Antagonistic RNA aptamer specific to a heterodimeric form of human interleukin-17A/F." Biochemie, 93 (2011): 1081-1088.
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