Aptamer Details

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MUC1 (MA3) (ID# 7725)

Aptamer Chemistry: DNA

Target: MUC1

Antigen/Target Category: Protein

Affinity (Kd): 38.3 nM (reported value)

Binding Conditions/Buffer: Binding Buffer: Hanks buffer with 0.1 mg/ml salmon sperm DNA and 1 mg/ml BSA.

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Comments: See also MUC1 (S1.6).

Sequence ():

Length: 86

Molecular Weight: 26266.08

Extinction Coefficient: 827500

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Y Hu et al. Novel MUC1 aptamer selectively delivers cytotoxic agent to cancer cells in vitro. PLoS ONE 7(2012): e31970.

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