Aptamer Details

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Periostin Aptamer (PNDA-3) (ID# 7890)

Aptamer Chemistry: RNA

Target: Periostin

Antigen/Target Category: Protein

Affinity (Kd): 1.07 nM (reported value)

Binding Conditions/Buffer: 40 mM/1 HEPES, 102 mM/1 NaCl, 5 mM/1mol/1g Cl2,5 mM KCl

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Comments: 5' benzylaminocarbonyl-d U modification

Sequence ():

Length: 51

Molecular Weight: 15666.2

Extinction Coefficient: 483400

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Lee, Y., Kim, I., Park, S., Kim, Y., Wu, S., Lee, J., Noh, D., Kim, K., Ryu, S. and Suh, P. "Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis." The American Society of Gene & Cell Therapy 21.5 (2013): 1004-13.

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