Aptamer Details

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PSA-1 (ID# 8202)

Aptamer Chemistry: DNA

Target: PSA (glycosylated)

Antigen/Target Category: Protein

Affinity (Kd): 177 +/-65 nM (reported value)

Binding Conditions/Buffer: PBS

Binding Temp: 25°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: N/A

Comments: Selection was performed in 1x PBS at 25 °C and 1300 rpm

Sequence ():

Length: 40

Molecular Weight: 12422.09

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Diaz-Fernandez, A, et al. "Focusing aptamer selection on the glycan structure of prostate-specific antigen: Toward a more specific detection of prostate cancer." Biosensors and Bioelectronics, 128 (2019): 83-90. doi: https://doi.org/10.1016/j.bios.2018.12.040

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