Aptamer Details

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TfRA4 (ID# 8192)

Aptamer Chemistry: DNA

Target: TfR-positive cells

Antigen/Target Category: Protein

Affinity (Kd): 487.3 ±108.8 nM nM (reported value)

Binding Conditions/Buffer: N/A

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: N/A

Sequence ():

Length: 14

Molecular Weight: 4338

Extinction Coefficient: 146

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Macdonald, J., Houghton, P., Xiang, D., Duan, W., & Shigdar, S. (2016). Truncation and Mutation of a Transferrin Receptor Aptamer Enhances Binding Affinity. Nucleic Acid Therapeutics, 26(6), 348–354. doi:10.1089/nat.2015.0585

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