Aptagen, LLC
V5 (ID# 8187)
DNA
Ovarian cancer vessels
Tissue
PBS with 5 mM MgCl2
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
highly specific to blood vessels present in and around the tumor tissue of high-grade serous ovarian cancer (HGSC) lines
5'-dCsdGsdCsdTsdCsdGsdGsdAsdTsdCsdGsdAsdTsdAsdAsdGsdCsdTsdTsdCsdGsdCsdAsdTsdAsdGsdAsdCsdCsdCsdAsdGsdCsdTsdGsdGsdTsdCsdCsdGsdGsdAsdAsdAsdAsdTsdAsdAsdGsdAsdTsdGsdTsdCsdAsdCsdGsdGsdAsdTsdCsdCsdTsdCsdTsdAsdGsdAsdGsdCsdAsdCsdTsdGs-3'
74
22730.10
719271
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Wang, Hongyu et al. “Morph-X-Select: Morphology-based tissue aptamer selection for ovarian cancer biomarker discovery.” BioTechniques vol. 61,5 249-259. 1 Nov. 2016, doi:10.2144/000114473
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