Aptamer Details

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VEGF receptor KDR and Flt-1 (v107) (ID# 7631)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.

Aptamer Chemistry: Peptide

Target: VEGF receptor KDR and Flt-1

Antigen/Target Category: Cells

IC50: 0.6 µM (reported value)

Binding Conditions/Buffer: Binding Buffer (0.5% (v/v) Tween20, 0.5% BSA in PBS)

Binding Temp: N/A°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 19

Molecular Weight: 2606.94

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Pan et al. "Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor." J Mol Biol, 316(2002): 769-787.

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