Aptagen, LLC
DNA
8-OHdG
Other
0.1 nM (reported value)
50 mM Trisƒ??HCl (pH 7.6), 300 mM NaCl, 30 mM KCl, and 5 mM MgCl2
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
8-OHdG (22) (ID# 302)
5'dTpdApdApdTpdApdCpdGpdApdCpdTpdCpdApdCpdGpdTpdApdTpdApdGpdGpdGpdApdApdTpdTpdCpdGpdTpdCpdGpdApdCpdGpdGpdApdTpdGpdCpdGpdGpdGpdCpdGpdApdTpdCpdGpdGpdCpdGpdGpdGpdGpdGpdGpdTpdGpdCpdGpdTpdGpdCpdGpdCpdTpdCpdTpdGpdTpdGpdCpdCpdApdGpdGpdGpdGpdGpdTpdGpdGpdGpdApdCpdApdGpdApdTpdCpdApdTpdApdTpdGpdGpdGpdGpdGpdTpdGpdCpdTpdCpdApdGpdGpdTpdCpdGpdApdCpdGpdCpdApdTpdGpdCpdGpdCpdCpdGp3'
121
37780.41 g/mole
1161100 L/(mole·cm)
63.64%
0.86
32.54
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Miyachi, Y. (2009). Selection of a dna aptmaer that binds 8-ohdg using gmp-agarose. Bioorganic & Medicinal Chemistry Letters, 19(2009), 3619-3622.
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